Posttranscriptional changes in growth factor-inducible gene regulation caused by antiproliferative interferons.
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چکیده
منابع مشابه
Regulation of the Egr-1 gene by tumor necrosis factor and interferons in primary human fibroblasts.
Treatment of quiescent primary human fibroblasts with tumor necrosis factor (TNF) alpha, TNF-beta, interleukin-1, interferon (IFN) alpha, IFN beta, or IFN gamma induced Egr-1 mRNA. In primary human fibroblasts TNF-alpha and TNF-beta were mildly mitogenic and IFN alpha and IFN gamma were growth inhibitory. However, in HeLa cells TNF but not IFN induced the expression of Egr-1 mRNA, while both cy...
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ژورنال
عنوان ژورنال: Cell Regulation
سال: 1990
ISSN: 1044-2030
DOI: 10.1091/mbc.1.2.215